Evaluation of Blood Sugar Lowering Property of Aqueous Extract of Ximenia Americana in Allaxon Induced Diabetic Rats

Diabetes mellitus (DM) is a chronic disease caused by insufficient production of insulin by pancreatic gland and decrease in absorption glucose by the muscles in the systems and caused increase the concentration of glucose in blood [1]. It is also produced due to the hereditary characters. Due to increase glucose level in blood causes various deficiencies and hampers the normal Physiological effects of the human system like blood vessels and nerves system etc [2]. It is projected that the diabetic is the main disease which can increase the deaths retain next coming 25 years in Asian committee and Africans [3]. Now days there are many allopathic drugs are available to treat this disease. But all these agents causing serious side effects after prolong use. Hence to overcome these adverse effects such as Hematological effects, coma, disturbance of liver and kidney etc [4]. Hence many traditional plants medicines are using throughout the world to treat the diabetic diseases [5]. When compared with synthetic drugs, the plant drugs have less toxic effects with fewer side effects [6]. Ximenia Americana is commonly known as Mogi. In Indian system of Medicine, the various plants parts like leaves, fruits etc are using treat the diabetes, mouth ulcers etc [7]. Hence the present investigation was under taken to evaluate the antidiabetic activity of aqueous extract of leaves of Ximenia Americana in a Alloxan induced diabetic rates to confirm the pharmacological evidence in support of Folklore claim [8].